AmpC ?-lactamases producing escherichia coli and klebsoella pneumoniae:a survey and analysis
- VernacularTitle:大肠埃希菌及肺炎克雷伯菌中AmpC酶的检测
- Author:
Yongxiang XIA
;
Weiwen WANG
- Publication Type:Journal Article
- Keywords:
Extended-spectrum ?-lactamases;
AmpC lactamases;
Escherichia coli;
Klebsoella pneumoniae
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect AmpC ?-lactamases from clinical isolates of escherichia coli and klebsoella pneumoniae in our hospital.Methods Using confirmatory test recommended by the NCCLS to detect ESBLs producing escherichia coli and klebsoella pneumoniae.Adopting three dimensional extract test and three dimensional depression test to detect AmpC ?-lactamases.Results Among 236 escherichia coli strains collected,104 were ESBLs producing strains.Among 135 klebsoella pneumoniae strains collected,29 were ESBLs producing strains.Among 106 cefoxitin-resistant strains,AmpC ?-lactamases producing strains were found in 3 strains.Conclusion ESBLs are the most important resistant mechanisms of the two bacteria isolates in our hospital.The strains cefoxitin-resistant may result from the loss of the membrane porin.
