Clinical Effect of Combination of Kurarinone and Thymosin ?_1 on Patients with Chronic Hepatitis B.
- VernacularTitle:苦参素联合?_1胸腺肽治疗慢性乙肝78例临床观察
- Author:
Fang HUANG
- Publication Type:Journal Article
- Keywords:
Kurarinone;
Thymosin ?_1 for injection;
Chronic hepatitis B
- From:
Journal of Medical Research
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical effect of combination of kurarinone and thymosin ?_1 for injection in treating chronic hepatitis B.Method One hundred and fifty-six patients with chronic hepatitis B were randomized into two groups,additional KR combined thymosin ?_1 for injection was given to treated group,and KR to control group.The therapeutic course for them was 6 months.We compared the serum ALT、 hepatitis B virological markers、T lymphocyte response before and 6 months after treatment.Results After treatment,the results showed that the levels of CD_3+、CD_4+、CD_4+/CD_8+ T cell in CHB patients of treatment were much higher than control groupnt.The ratio HBeAg and HBV-DNA loss were increased,the difference was significant(P
