Detection of seral p53 antibody in patients with breast carcinoma by immuno-polymerase chain reation
- VernacularTitle:PCR法检测乳腺癌患者血清抗p53蛋白抗体的研究
- Author:
Jie LI
- Publication Type:Journal Article
- Keywords:
PCR;
Breast carcinoma;
Anti-p53 antibody
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To present a new seriological method for diagnosing breast carcinoma.Methods Seral anti-p53 antibody was detected with immuno-polymerase chain reation(Immuno-PCR).The expression of p53 in tissue was detected with enzymeimmu-nohistochemistry technique.Results The positive rate of anti-p53 antibody in serum of breast carcinoma was 39.5% and anti-p53 antibody was not found in non-carcinoma and normal controls.The positive rate of anti-p53 antibody was higher than that of non-carcinoma and normal controls(P
