The exploration of antibiotic therapy in neutropenic hematological maligence patients
- VernacularTitle:血液肿瘤患者粒细胞缺乏症合并感染的抗生素治疗
- Author:
Liping PANG
;
Qingxiang MENG
;
Jin LIU
;
Hongyu ZHANG
;
Yinghui WEI
- Publication Type:Journal Article
- Keywords:
Hematological maligence;
Neutropenia;
Antibiotic therapy
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the efficiency and safety of regimens of empiric antibiotic therapy in neutropenic hematological maligence patients.Methods The clinical data of empiric antibiotic therapy for 260 febrile episodes in 125 neutropenic hematological maligence patients were analyzed retrospectively.Results A total of 45 febrile episodes were treated with tazocin plus amikacin(regimen TA).80 episodes were treated with ceftazidime plus amikacin(regimen CA),75 episodes with imipenem plus amikacin(regimen IA) and 60 episodes with maxipime plus amikacin(regimen MA).The medians of initial therapy in each regimen were 7～8 days.Percentage of satisfactory response had no significant difference in episodes treated with regimens TA,IA and MA(65%,70% and 79% respectively),and it was better than regimen CA(P
