Blood coagulation disorder in acute pancreatitis of the elderly
- VernacularTitle:老年急性胰腺炎患者血浆凝血功能异常的研究
- Author:
Guoan ZHENG
;
Huawei CHEN
- Publication Type:Journal Article
- Keywords:
Elderly;
Acute pancreatitis;
Fibrinogen;
Prostaglandin E_1
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the significance of blood coagulation disorder in acute pancreatitis(AP) of the elderly and its treatment with prostaglandin E_1.Methods Prothrombin time(PT),partially activated thromboplastin time(APTT) and fibrinogen(FIB) in cases of AP with ages over 60 were checked and compared with those in groups of AP with ages under 60 and normal control subjects.10 cases of AP of the elderly with elevated FIB were treated with prostaglandin E_1.Results Compared with groups of AP with ages under 60 and the normal subjects,FIB was significantly higher in cases of AP of the elderly with the highest in patients of SAP.8 out of 10 aged AP patients with elevated FIB was successfully treated with prostaglandin E_1.Conclusion Patients of AP may present with blood coagulation disorders especially in aged patients.Aged patients with elevated fibrinogen may predispose to SAP.Prostaglandin E_1 may be effective in this occasion.
