The change of contents of blood serum TNF-? and IL-8 of alcoholic fatty liver
- VernacularTitle:酒精性脂肪肝大鼠血清TNF-?、IL-8水平的变化
- Author:
Yusheng ZHOU
;
Xuefeng YANG
- Publication Type:Journal Article
- Keywords:
Alcoholic fatty liver;
TNF-?;
IL-8
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To abserve the change of contents of blood serum TNF-? and IL-8 of alcoholic fatty liver rats.Methods To observer the change of serum activities of alanine aminotransferase(ALT),and serum contents of tumor necrosis factor(TNF)-?,interleukin(IL)-8 and hepatic histopathology observed by microscope,which the rats with alcoholic fatty liver were fed by high lipid food and drunk 10% alcohol qd?10 weeks.Results The model group rats' liver became more fatty and activities of ALT,and the contents of TNF-? and IL-8 in blood serum were higher than the normal group rats and there was significant difference(P