Study of clinical value and influencing factors of ~1H-MR spectroscopy in mammary tumors
- VernacularTitle:MR氢质子波谱在乳腺肿块应用中的价值及技术干扰因素分析
- Author:
Bin ZHAO
;
Shifeng CAI
;
Taifei YU
;
Hongjuan PENG
;
Huihua LI
- Publication Type:Journal Article
- Keywords:
Breast diseases;
Breast neoplasms;
Magnetic resonance spectroscopy;
Pathology
- From:
Chinese Journal of Radiology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic value of 1H magnetic resonance spectroscopy (1H-MRS) in mammary tumors and to discuss the technique factors which influence the detection rate.Methods The 1H-MRS features of 47 mammary tumors, of which 24 malignant tumors and 23 benign tumors confirmed by pathology were analyzed. All of the tumors were detected before Gd-DTPA enhancement. Results Eleven of 24 malignant tumors showed increased choline resonance peak at 3.24 ppm while 4 of 23 benign ones at 3.24 ppm .The positive value were 45.8% and 17.4% respectively. The sensitivity and specificity were 45.8% and 82.6% respectively by using 1H-MRS to discriminate benign from malignant tumors. The main factors influencing the detection rate were low suppressed lipid, low suppressed water and low single-noise rate.Conclusion Choline is not special features of malignant tumors. Choline can be obtained despite the nature of tumor if they grow rapidly. The low sensitivity of choline to be detected mainly dues to technique factors.
