Analysis of risk factors for nosocomial pneumonias due to ESBLs-producing Klebsiella pneumoniae.
- VernacularTitle:产超广谱?内酰胺酶肺炎克雷伯菌医院获得性肺炎临床危险因素分析
- Author:
Congrong LI
;
Qingquan LI
- Publication Type:Journal Article
- Keywords:
Klebsiella pneumoniae;
Extended-spectrum ?-lactamases;
Risk factor
- From:
Chinese Journal of Practical Internal Medicine
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze risk factors of nosocomial pneumonias due to ESBL-producing Klebsiella pneumoniae.Methods From July 2001 to December 2004,38 patients with ESBL-producing K. pneumoniae and 63 patients with non-ESBL-producing K. pneumoniae were enrolled. ESBL-producing strains were detected by confirmed test.Results Hospital duration,ICU stay,tracheal intubation or tracheotomy,indwelling catheters,mechanical ventilation and use of cefotaxime were found to be risk factors in the acquisition of K. pneumoniae with ESBLs by univariate analysis. Cefotaxime use remained as risk factors by multivariate analysis with logistic regression. Conclusion The reasonable use of cefotaxime is an important measure to control the prevalence of ESBLs-producing strains of Klebsiella pneumoniae.