The study of relationship between insulin resistance and dyslipidemia in type 2 diabetes associated with nonalcoholic fatty liver
- VernacularTitle:2型糖尿病合并非酒精性脂肪肝与胰岛素抵抗及血脂紊乱关系研究
- Author:
Shuhui YANG
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,non-insulin-dependent;
Fatty liver;
Dyslipidemia;
Insulin resistance
- From:
Chinese Journal of Primary Medicine and Pharmacy
2005;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between insulin resistance(IR) and dyslipidemia and nonalcoholic fatty liver disease(NAFLD) in type 2 diabetes mellitus(T2DM).Methods Seventy-two patients were divided into fatty liver group and non-fatty liver group.Blood lipid,blood glucose(BG),blood pressure,fasting and 2-hour serum insulin were measured.At the same time,HOMA-IR,body weight index(BMI),the waist hip ratio(WHR) were calculated.the diagnosis of the fatty liver was learned from the check according to an image.Results Compared with the non-fatty liver group,the average levels of TG,LDL-C,FIns,2hIns,HOMA-IR,BMI,WHR,alanine aminotransferase(ALT),?-glutamyl transpeptidase(?-GT),uric acid and diastolic pressure were significantly higher in fatty liver group(P0.05).Conclusion Compared with the non-fatty liver patients,T2DM patients complicated with NAFLD have more serious IR,dyslipidemia and obesity.It indicates that IR has a significant influence on the outbreak of the fatty liver;The NAFLD is probably one of components of metabolic syndrome.
