Serum levels of chemoattractants high-sensitivity Creactive protein and neopterin with acute coronary syndrome and their clinical significance
- VernacularTitle:急性冠状动脉综合征患者血清高敏C反应蛋白和新蝶呤的检测及意义
- Author:
Zhi CHENG
;
Mingding TAN
;
Dequan ZHANG
- Publication Type:Journal Article
- Keywords:
Coronary artery disease;
C-reactive protein;
Neopterin
- From:
Chinese Journal of Primary Medicine and Pharmacy
2005;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the change of the inflammatory marker high-sensitivity C-reactive protein(HS-CRP) and the immune marker neopterin in patients with acute coronary syndrome(ACS).Methods The study population included 40 patients with acute myocardial infarction(AMI) and 40 patients with unstable angia pectons(UAP).At the same time,we selected 80 patients with chronic stable angia pectons.Serum levels of HS-CRP,neopterin were measured by means of ELISA.Results HS-CRP and neopterin were significantly higher in acute coronary syndrome group than those in chronic stable angina group.Conclusion HS-CRP and Neopterin are elevated in acute coronary syndrome.They can be used as the certain diagnosetic value for ACS.This study also supports the hypothesis that both immune and inflammation play roles in ACS.
