The relationship between the expression of vascular endothelial growth factor and it's acceptor and microvessel density with the clinicopathological features of breast carcinoma
- VernacularTitle:微血管密度、抑血管内皮生长因子及其受体表达与乳腺癌临床病理因素的关系
- Author:
Liping LIU
;
Guanghui HUANG
;
Chenglin LIU
- Publication Type:Journal Article
- Keywords:
Breast carcinoma;
Microvessel density;
Vascular endothelial growth factor;
Immunohistochemistry
- From:
Chinese Journal of Primary Medicine and Pharmacy
2005;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the prognosis value of the expression of vascular endothelial growth factor and it's acceptor(VEGF,Flk-1) and microvessel density(MVD) gene proteins in the breast carcinoma and paracarcinoma tissue.Methods Immunohistochemical technique was adopted to detect the protein expression of VEGF,Flk-1 and MVD in 76 cases of breast carcinoma and 10 cases paracarcinoma tissue.Results (1)The positive expression of VEGF,Flk-1 were 59.3% and 61.3% in the carcinoma group,which were higher than in the paracarcinoma tissue(P
