Gene expression of nuclear receptor corepressor in androgen independent prostate cancer and its clinical significance
- VernacularTitle:核受体辅阻遏子在雄激素非依赖性前列腺癌中的表达及临床意义
- Author:
Daoju GAN
- Publication Type:Journal Article
- Keywords:
prostatic neoplasma;
carcinoma;
NCoR;
immunohistochemistry
- From:Journal of Third Military Medical University
1983;0(03):-
- CountryChina
- Language:Chinese
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Abstract:
Objective To explore the gene expression of nuclear receptor corepressor(NCoR) in androgen independent prostate cancer(AIPC) and its clinical significance.Methods The expression of NCoR and androgen receptor(AR) was detected by two-stage immunohistochemical method in 15 cases with AIPC,20 cases with androgen dependent prostate cancer(ADPC) and 20 cases with benign prostatic hyperplasia(BPH) respectively.Results The rate of NCoR expression in AIPC,ADPC and BPH was 20%,80% and 95% respectively and the difference of NCoR expression between AIPC and ADPC,BPH was significant(P
