Association between NADPH oxidase subunit p22phox gene polymorphism and type 2 diabetic nephropathy patients in Shanghai
- VernacularTitle:2型糖尿病肾病患者p22phox基因多态性的研究
- Author:
Lianyong LIU
;
Dajin ZOU
;
Jun ZHANG
- Publication Type:Journal Article
- Keywords:
Type 2 diabetes mellitus;
Diabetic nephropathy;
NADPH oxidase;
Gene polymorphism
- From:
Chinese Journal of Nephrology
1994;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). Logistic multiple regression analysis showed T242 allele, body mass index, fasting blood glucose, HbAlc, Homa-IS, systolic blood pressure were risk factors of type 2 diabetic nephropathy. Conclusions p22phox C242T gene polymorphism is associated with diabetic nephropathy in Shanghai people. p22phox subunit T allele mutation is pnobabaly one of predisposing genes of type 2 diabetic nephropathy, and p22phox A640G gene polymorphism is not associated with diabetic nephropathy in Shanghai people. T242 allele, fasting blood glucose, HbAlc, Homa-IS, systolic blood pressure are risk factors of type 2 diabetic nephropathy.
