Study on the level of lipopolysaccharide binding protein in serum of patients with chronic viral hepatitis
- VernacularTitle:慢性病毒性肝炎患者血清内毒素结合蛋白的临床意义
- Author:
Zhijun SU
;
Ruyi GUO
;
Xiaodong QIU
- Publication Type:Journal Article
- Keywords:
Hepatitis B, chronic;
Endotorins;
Carrier proteins
- From:
Chinese Journal of Infectious Diseases
1999;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between lipopolysaccharide binding protein(LBP) in serum and degree of hepatic inflammation. Methods The levels of LBP in serum of 99 patients with chronic viral hepatitis (CVH) were detected by ELISA. The levels of LBP in 33 of all patients with chronic severe viral hepatitis were further detected 2~4 weeks after treatment. Results The serum levels of LBP in patients with chronic viral hepatitis were higher than that in normal patients [(79.62?45.52) ng/ml vs (50.22?31.44) ng/ml, P=0.001]. The serum levels of LBP in patients with chronic severe viral hepatitis were significantly higher than that in patients with moderate degree CVH group, severe degree CVH group, and normal group (P