HEMOSTATIC ABNORMALITIES AND ENAOTOXEMIA IN HEPATIC CIRRHOSIS
- VernacularTitle:肝硬化患者凝血障碍与内毒素血症
- Author:
Lili DAI
- Publication Type:Journal Article
- Keywords:
Coagulation abnormalities;
Limulus lysated assay;
Endotoxemia;
Fibronectin
- From:
Journal of Chongqing Medical University
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
A follow-up study of the dynamic changes with multiple parameters of blood coagulation and plasma limulus assay was carried out in 20 patients with decompen-sated hepatic cirrhosis.It was found that the levels of endotoxin in peripheral blood and factor VIII-related antigen increased significantly, prothrombin time and kaolin partial thromboplastin time prolonged, whereas fibrinogen, factor II, hepaplastin test, antithrombin-III and fibronectin decreased.Our data suggested that( 1 )both the coagulation abnormalities and endotoxemia were coexisted and correlated progressively with the disease process. ( 2 )the incidence and severity of endotoxemia were closely correlated with the degree and severity of hepatic decompensation; ( 3 )dynamic charges of endotoxemia and coagulation abnormalities were of some prognostic significance in decompensated hepatic cirrhosis
