Prothrombotic state in ulcerative colitis and the relationship with phase,severity and truelove classification
- VernacularTitle:溃疡性结肠炎血栓前状态与病期、内镜分级的关系
- Author:
Li YING
;
Chunmeng JIANG
;
Zhaohui WANG
;
Yan YAN
- Publication Type:Journal Article
- Keywords:
Colitis,ulcerative;
Endoscopes,gastriontestinal
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the prothrombotic state of patients with ulcerative colitis(UC) and the relationship with phase,severity and Truelove classification.Methods 97 patients with UC were grouped by non-active phase and active phase;The latter were subdivided into mild,moderate and severe degree by clinical manifestation and TrueloveⅠ,Ⅱ,Ⅲ via endoscopy,vWF activity,fibrinogen and D-dimer were detected in all patients.Results vWF activity,fibrinogen and D-dimer were markedly higher in active phase than in non-active phase(t=14.137,3.435,3.625,respectively).There were no significant difference in vWF activity,fibrinogen and D-dimer between mild,moderate and severe degree and Truelove Ⅰ,Ⅱ,Ⅲ.Conclusion Prothrombotic state including hypercoagulation and secondary fibrinolysis correlates with the clinical phase of UC significantly.
