Relationship between maternal hepatic function and fetal prognosis in intrahepatic cholestasis of pregnancy
- VernacularTitle:妊娠期肝内胆汁淤积症孕妇肝功能指标与围生儿预后的关系
- Author:
Xiaomin FU
;
Qing JIANG
;
Shulan WANG
;
Rongli XUE
- Publication Type:Journal Article
- Keywords:
Pregnancy;
Cholestasis,intrahepatic;
Liver function tests;
Infant
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relation between hepatic function of mothers and prognosis of fetuses in intrahepatic cholestasis of pregnancy(ICP).Methods 166 patients with ICP were retrospectively studied.Results The incidences of meconium passage and fetal distress were perfectly high in mothers of high serum transaminase and bilirubin.The birth weight and Apgar scores of neonate were related to the levels of bilirubin and we could predict the fetal prognosis by analysis of mother's serum bilirubin level.The serum total bile acid(TBA) levels and other hepatic indexes were not related to the incidences of meconium passage and fetal distress.Conclusions The fetal prognosis of mothers with high-level serum transaminase and bilirubin is bad,so they must be taken great aware of.The prognosis of fetuses can be bettered by cesarean section at proper time.
