Inhibition of lung cancer cells of primary culture and A549 cell line on the proliferation of tumor-infiltrating lymphocytes in vitro
- VernacularTitle:肺癌原代细胞和细胞系A549对肿瘤浸润性淋巴细胞体外增殖的抑制作用
- Author:
Guoqiang ZHANG
;
Yaoguang JIANG
;
Ruwen WANG
;
Yidan LIN
- Publication Type:Journal Article
- Keywords:
lung cancer cell;
A549 cell;
tumor infiltrating lymphocyte;
inhibition
- From:Journal of Third Military Medical University
1984;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the inhibition of lung cancer cells of primary culture and A549 cell line on the proliferation of tumor-infiltrating lymphocytes(TIL) in vitro and its clinical implications.Methods Human lung cancer cells and TILs were isolated from 8 cases of primary lung cancer and cultured.The inhibition of isolated human cancer cells and A549 cells to TILs was detected by MTT method.Results Lung cancer cells of primary culture and A549 cells can kill TILs to various degrees.Conclusion Inhibition of lung cancer cells to TIL may be one of the mechanisms of immune escapes.
