Change of the levels of plasma anti-Ⅹa,anti-Ⅱa in acute coronary syndromes and the influence of low-molecular-weight heparin on plasma anti-Ⅹa and anti-Ⅱa levels
- VernacularTitle:急性冠脉综合征患者抗Ⅹa因子、抗Ⅱa因子的变化及低分子质量肝素的干预作用
- Author:
Wei WANG
;
Baogui SUN
;
Qiuyan DAI
- Publication Type:Journal Article
- Keywords:
Acute coronary syndromes;
Low-molecular-weight heparin;
Anti-Ⅹa
- From:
Chinese Journal of Practical Internal Medicine
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the change of the levels of plasma anti-Ⅹa,anti-Ⅱa in acute coronary syndromes and the influence of low-molecular-weight heparin(LMWH)on plasma anti-Ⅹa and anti-Ⅱa levels.Methods Plasma anti-Ⅹa and anti-Ⅱa were measured with the specific chromogenic substrate in 24 patients with ACS and 10 healthy controls from Jan.2003 to Sep.2003.LMWHs were administrated to the ACS patients.Plasma anti-Ⅹa and anti-Ⅱa were measured immediately,and at 4 h,24 h,and day 7 after initial injection.Results Plasma anti-Ⅹa and anti-Ⅱa levels in ACS patients were significantly higher than those in controls(P