Effects of restraint stress on behaviors of mice with focal cerebral ischemia
- VernacularTitle:束缚应激对局灶性脑缺血小鼠行为的影响
- Author:
Jun GUO
;
Li LIU
- Publication Type:Journal Article
- Keywords:
brain cerebral ischemia;
restraint stress;
depressive disorders
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effects of restraint stress on behaviors of mice with focal cerebral ischemia. Methods Male mice were first subjected to left middle cerebral artery occlusion/reperfusion. Repeated restraint stress (2 hours/day for 2 weeks) was given from 1 week after surgery. At the end of stress scheme, sucrose solution consumption test, open-field test and forced swimming test were performed. Results Spontaneous locomotor activity and coordination test were decreased to the lowest level on the 1st day after MCAO compared with the baseline values before surgery (P
