Renal potassium wasting and hypocalciuria ameliorated with magnesium repletion in Gitelman's syndrome.
10.3346/jkms.1997.12.2.157
- Author:
Young Jung CHO
1
;
Geun Tae PARK
;
Yun Ju CHO
;
Ho Jung KIM
Author Information
1. Department of Internal Medicine, Hanyang University Kuri Hospital, Korea.
- Publication Type:Case Report
- MeSH:
Bartter's Disease/urine;
Bartter's Disease/therapy*;
Bartter's Disease/blood;
Calcium/urine*;
Case Report;
Female;
Food, Fortified;
Human;
Hypokalemia/therapy*;
Magnesium/blood*;
Middle Age;
Syndrome
- From:Journal of Korean Medical Science
1997;12(2):157-159
- CountryRepublic of Korea
- Language:English
-
Abstract:
A woman aged 45 years was presented with hypokalemic metabolic alkalosis and hypomagnesemia associated with renal potassium and magnesium wasting. Her 24-hour urinary calcium excretion was strikingly low despite normocalcemia and normal creatinine clearance, which is one of characteristic findings of Gitelman's syndrome (GS). She was evaluated for the responses following Mg supplementation for 10 days, which showed marked increments in serum potassium and magnesium as well as improvements of the degree of renal potassium wasting and hypocalciuria. This amelioration of abnormal biochemical pictures in this patient after Mg supplementation proposes that the hypokalemia with renal potassium wasting and hypocalciuria may be caused by abnormal Mg metabolism.
