Clinical trial on the effect of leflunomide in treating refractory nephropathy syndrome
- VernacularTitle:来氟米特治疗难治性肾病综合征60例临床研究
- Author:
Cheng WANG
;
Tanqi LOU
;
Hua TANG
- Publication Type:Journal Article
- Keywords:
Leflunomide Refractory nephropathy syndrome
- From:
Chinese Journal of Practical Internal Medicine
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of leflunomide and prednisone in treating refractory nephropathy syndrome.Methods The 60 refractory nephropathy patients in our hospital from Oct,2000 to May,2003 were divided into two groups at random.Paients in test group received leflunomide and prednisone.Patients in control group received mycophenolate mofetil and prednisone.Clinical data were observed in the 2nd,4th,6th,8th,12th,16th,20th,24th and 28th week.Results After receiving leflunomide therapy in the test group,the proteinuria was decreased significantly(P0.05),but rate of showing efficacy in 12th week in Leflunomide group was higher than mycophenolate mofetil group(P
