Preliminary study of normal changes in brain white matter during childhood with diffusion tensor imaging
- VernacularTitle:应用扩散张量成像对正常儿童脑白质发育的初步研究
- Author:
Jiangxi XIAO
;
Xuemei GUO
;
Sheng XIE
;
Xiaoying WANG
;
Xuexiang JIANG
- Publication Type:Journal Article
- Keywords:
Diffusion;
Magnetic resonance imaging;
Developmental disabilities;
Child
- From:
Chinese Journal of Radiology
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the normal changes in brain white matter during childhood by analyzing the anisotropy of different regions and different age groups with diffusion tensor imaging (DTI). Methods DTI was performed in 89 children (age range from 2 days to 18 years) without brain abnormalities, and the data measured in fractional anisotropy(FA) maps were analyzed statistically. Children less than 6 months were ranged to group 1, 6-12 months to group 2, 1-3 years to group 3, 3-5 years to group 4, 5-8 years to group 5, 8-12 years to group 6, 12-18 years to group 7. Results (1) There were significant differences in anisotropy (FA values) among different regions of white matter in brain In group 7, the FA value of corpus callosum was 0.826?0.039, middle cerebellar peduncle 0.678?0.043, frontal white matter 0.489?0.033. (2) The anisotropy among different age group was statistically different, P
