Anticancer effects of PPAR? agonists:recent progress
- VernacularTitle:PPAR?激动剂抗肿瘤作用的研究进展
- Author:
Yanming ZHOU
;
Zhengfeng YIN
;
Jiamei YANG
- Publication Type:Journal Article
- Keywords:
peroxisome proliferator-activated receptor;
PPAR? agonists;
antineoplastic agents
- From:
Academic Journal of Second Military Medical University
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Peroxisome proliferator-activated receptor(PPAR) belongs to the superfamily of nuclear hormone receptor.Three PPAR subtypes have been identified to date(PPAR?,PPAR? and PPAR?)and the relationship between PPAR? and tumor has drawn great attention.Current data showed that PPAR? agonists exert their antineoplastic effect through inhibiting cell growth and angiogenesis,inducing cell apoptosis and differentiation,and reducing tumor invasive ability.PPAR? agonists may be a promising tool for cancer chemotherapy.
