The proliferative effect of aloe coarse polysaccharide on the cultured epidermal cells in vitro
- VernacularTitle:芦荟粗多糖对体外培养人表皮细胞增殖作用的研究
- Author:
Xiaodong CHEN
;
Boyu WU
;
Qiong JIANG
;
Xinhua LIN
;
Liying HUANG
;
Zhongcheng WANG
- Publication Type:Journal Article
- Keywords:
aloe coarse polysaccharid;
epidermal cells;
proliferation;
intracellular calcium;
lactate dehydrogenase
- From:
Chinese Pharmacological Bulletin
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim To investigate the effects of aloe coarse polysaccharid on proliferation and the intracellular calcium level and the leakage rate of lactate dehydrogen-ase(LDH) of the epidermal cellsin vitro.Methods The epidermal cells were treated with aloe coarse po-lysaccharid of75,150,300,600 and 1 200 mg.L-1respectively.The proliferation of epidermal cells wasobserved interms of the proliferation curve and the pop-ulation doubling/day(PD/d).The concentration ofintracellular calcium and the leakage rate of LDHwerealso measured.Results In aloe coarse polysaccharidgroup,a dose-dependent and statistically significant(P
