The level of IL-12 and IL-10 in the serum of patients with progressive psoriasis vulgaris and their clinical significances
- VernacularTitle:寻常性银屑病患者血清白介素-12及白介素-10的水平检测和临床意义
- Author:
Tuanqi FAN
;
Weihong LI
- Publication Type:Journal Article
- Keywords:
Psoriasis;
Interleukin-12;
Interleukin-10
- From:
Chinese Journal of Primary Medicine and Pharmacy
2005;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the level of interleukin(IL)-12 and IL-10 in the serum patients with progressive psoriasis vulgaris and to investigate the role them. Methods The serum samples were collected from 10 patients with progressive psoriasis vulgaris. The levels of IL-12 and IL-10 in the serum both the patients and health controls were detected by ELISA. Results IL-12 level increased significantly and IL-10 decreased remarkably in the patients compared with the control. Conclusion IL-12 and IL-10 play an important role in pathogenesis of psoriasis vulgaris.