Hypofractionated three-dimensional conformal radiotherapy for primary liver cancer with portal vein tumor thrombosis
- VernacularTitle:原发性肝癌伴门脉癌栓的大分割三维适形放疗效果分析
- Author:
Xiaodong ZHU
;
Shixiong LIANG
;
Anyu WANG
;
Long CHEN
;
Haijie LU
- Publication Type:Journal Article
- Keywords:
Liver neoplasms/radiotherapy;
Tumor embolism,portal;
Radiotherapy,conformal;
Prognosis
- From:
Chinese Journal of Radiation Oncology
2005;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of hypofractionated 3DCRT for primary liver cancer(PLC) with portal vein tumor thrombosis(PVTT).Methods Between April 1999 and August 2003,34 PLC patients with PVTT received hypofractionated 3DCRT.The severity of hepatic cirrhosis was 23 in Child-Pugh gradeA and 11 gradeB.The median value of GTV was 773?cm~3(105-2097?cm~3).The radiotherapy regimen consisted of 38-63?Gy in 7-15 fractions with 4-8?Gy per fraction(median value 5?Gy),the treatment was delivered 3 times per week during every other day.Results Having response rate(CR+PR) of 76%(26/34),the overall 1-,2-,and 3-year survival rate at was 36%,19% and 13%,respectively.Conclusion Hypofractionated three-dimensional conformal radiotherapy is effective for primary liver cancer with portal vein tumor thrombosis.
