Clinical significance of the change of nuclear factor-?_B in frequently relapsed nephropathy syndrome
- VernacularTitle:频复发性肾病核转录因子?_B活性改变的临床意义
- Author:
Feixia DONG
;
Jinguo CHENG
;
Zhen HU
- Publication Type:Journal Article
- Keywords:
Frequent relapsed nephropathy syndrome Neutrophil Nuclear factor-?_B
- From:
Chinese Journal of Practical Internal Medicine
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical significance of the change of nuclear factor-?_B activity in frequently relapsed nephropathy syndrome.Methods 60 patients with FRNS were involved in the study,30 patients(at relapses)were regarded as test groups A,30 patients(at remission)were regarded as test groups B,30 healthy persons in group C(control group).8W after treatment,after separating neutrophil and distilling nuclear protein,we mensured the activation of nuclear factor -?_B by EMSA.Results Neutrophil nuclear factor -?_B has been activated at relapsed group,but the activity of nuclear factor -?_B in the remission group was lower than the relapsed group P
