The relationship between serum Leptin concentration and insulin resistance in type 2 diabetes
- VernacularTitle:2型糖尿病血清瘦素质量浓度与胰岛素抵抗的关系
- Author:
Yaru ZHOU
;
Zhanjian WANG
;
Jianhua PANG
- Publication Type:Journal Article
- Keywords:
Leptin Obesity Insulin resistance Diabetes
- From:
Chinese Journal of Practical Internal Medicine
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between serum Leptin levels and insulin resistance.Methods During 2001-10~2002-08 fasting serum Leptin concentrations were measured with RIA in 196 cases(including 118 type 2 diabetes,78 controls),and height,body weight were measured to calculate body mass index(BMI).Results HbA_1c,SBP,TG,Leptin were correlated with ISI,Leptin concentration were higher in type 2 diabetes than in controls;Leptin concentration was significantly increased in obese subjects,whereas in type 2 diabetes serum Leptin concentration had no significant difference between obese subjects and non-obese subjects.Conclusion Most of obeses subjects have insulin resistance,whether obesity or not,the patients type 2 diabetes have some kind of insulin resistance.
