Progress in research of inhibitive effects of RNAi against hepatitis virus infection
- VernacularTitle:RNAi抗肝炎病毒感染作用的研究进展
- Author:
Shuangmin ZHANG
;
Zhongdao WU
- Publication Type:Journal Article
- Keywords:
RNA interference;
hepacivirus;
viral infection
- From:
Academic Journal of Second Military Medical University
2000;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
RNA interference (RNAi) is an effective antiviral mechanism of human body. It is a sequence specific process involving post transcriptional gene silencing initiated by double stranded RNA (dsRNA) homologous to the silenced genes. RNAi,as a genomic immune phenomenon involving the modulation of specific gene expression and an efficient gene-level defense mechanism against viral infection,has become the focus of study in biomedicine. This review summarized the researches of RNAi in inhibiting hepatitis virus infection,analyzed the advantages of RNAi in clinical treatment of hepatitis,and pointed out the existing problems,hoping to provide references for antiviral study of hepatitis infection.
