Olfactory ensheathing cell transplantation in treatment of spinal cord injury:an update
- VernacularTitle:嗅鞘细胞移植治疗脊髓损伤的进展
- Author:
Xingwen XIE
;
Qi SHI
- Publication Type:Journal Article
- Keywords:
olfactory ensheathing cell;
cell transplantation;
spinal cord injuries
- From:
Academic Journal of Second Military Medical University
2000;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
The treatment of spinal cord injury is always a stubborn problem for neurosurgeons because nerve cell cannot regenerate by itself and the glia scar can prevent the axonal regeneration. Therefore, to decrease the neuron death and formation of scar and to increase axonal regeneration are the keys for clinical treatment. Many studies showed that the olfactory ensheathing cells(OEC) can promote axonal regeneration and prover axonal growth,bringing hope for treament of spine injury, but the result is not satisfactory in clinic. In order to improve the clinical effect of OES transplantation many studies combine it with genetic engineering and tissue engineering and some progress is made.