EFFECTS OF COMBINED ANTIOXIDANTS ON THE EXPRESSION OF CRP AND IL-6 IN TYPE 2 DIABETIC PATIENTS
- VernacularTitle:抗氧化剂对2型糖尿病人C-反应蛋白和IL-6表达的影响
- Author:
Songchao GUO
;
Cuifeng ZHU
;
Zhili ZENG
;
Qingxiang WU
;
Zuojie LUO
- Publication Type:Journal Article
- Keywords:
antioxidants;
CRP;
IL-6;
diabetic mellitus
- From:
Acta Nutrimenta Sinica
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effects of the cooperative actions of isoflavone, vitamin C and E on the expression of acute C reactive protein (CRP) and interleukin 6 (IL-6) in the patients with typeⅡdiabetic mellitus (DM). Method: Ninety six patients with DM were divided randomly into 4 groups, DM control group(B), and groups receiving low(C), medium (D) , and high (E) dose of the compound antioxidant of isoflavone, vitamin C and E respectively. Another 24 healthy subjects served as normal control group (A). Observe the changes of the levels of CRP and IL-6 during oral glucose tolerance test (OGTT). Results: The peak of serum levels of CRP and IL-6 in the patients of DM control group and lower dosage group appeared 1 h after OGTT and were significantly higher than the 0 h value (P
