STUDY ON THE CORRELATION BETWEEN SERUM LEPTIN AND LIPIDS LEVELS AND BREAST CANCER
- VernacularTitle:血清瘦素及脂类水平与乳腺癌的相关性研究
- Author:
Cunzhi HAN
;
Lili DU
;
Xiuying LIU
;
Jiexian JING
;
Xianwen ZHAO
;
Baoguo TIAN
- Publication Type:Journal Article
- Keywords:
leptin;
lipids;
breast cancer
- From:
Acta Nutrimenta Sinica
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). (2) The serum leptin and TG concentration in breast cancer group were significantly higher , the HDL level was significantly lower than those in the groups of breast benign disease and healthy control (P0.05).(3) Multiple logistic regression analysis reveal statistically significant association between serum leptin, TG , ApoA1 and HDL-C levels and breast cancer incident.(ORLeptin=1.14, 95% confidence interval CI:1.076-1.210, ORTG =2.663, 95% CI:1.65-6.82; ORApoA1=5.726, 95%CI : 1.238 - 26.480 and ORHDL=0.035, 95% CI : 0.007 - 0.162, respectively). Conclusion:The increased serum leptin and ApoA1 levels and decreased HDL-C level may be the risk factors of breast cancer.
