Change of discharge phase of!guinea pig hippocampal pyramidal cells during visual discriminative task
- VernacularTitle:豚鼠海马锥体细胞在视觉分辨任务中放电时相变化的初步研究
- Author:
Bo HU
;
Jianfeng SUI
;
Wei HUANG
;
Jun LUO
- Publication Type:Journal Article
- Keywords:
pyramidal cell;
wavelet transforms;
? rhythm;
spike potential
- From:Journal of Third Military Medical University
2003;0(19):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the change of discharge phase of guinea pig hippocampal CA1 pyramidal cells during visual discriminative task with an effective and convenient program we designed. Methods Five guinea pigs were performed by extracellular single unit recording in vivo when they were performing visual discriminative task. Discharge signals of individual pyramidal cells were extracted from different frequency signals by wavelet transform (WT), which made it feasible to calculate discharge phase of pyramidal cells in terms of time correlation between discharge and ? rhythm. Results The discharge phase of CA1 pyramidal cells in the 1 to 5s interval before visual discriminative task (172??1.8?) was obviously earlier than that in the 6 to 10s interval after visual discriminative task (189??3.7?) ( P0.01). Conclusion The program we designed is capable of detecting discharge phase of pyramidal cells. Regular shift of discharge phase of hippocampal CA1 pyramidal cells emerges before and after performing visual discriminative task.
