The role of TGF-?_1 and HGF in chronic hepatitis B with early renal impairment
- VernacularTitle:血清转化生长因子?_1及肝细胞生长因子与慢性乙型肝炎早期肾损害关系的研究
- Author:
Xinwen SONG
;
Cunliang DENG
;
Yunjian SHENG
- Publication Type:Journal Article
- Keywords:
Early renal impairment Chronic hepatitis B Cytokines
- From:
Chinese Journal of Practical Internal Medicine
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of transforming growth factor-?_1 (TGF-?_1)and hepatocyte growth factor(HGF)in the pathogenesis of early renal impairment in patients with chronic hepatitis B(CHB).Methods The serum levels of TGF-?_1 and HGF of 44 patients with CHB and 20 healthy people were measured by specific-ELISA,and the urine levels of ?_1-microglobulin (?_1-MG)and microalbumin (mALB)were tested by RIA.Results The serum levels of TGF-?_1 and HGF in the patients with CHB were significantly higher than those in the control (P
