Platelet recovery in patients with chronic idiopathic thrombocytopenic purpura after eradication of helicobacter pylori
- VernacularTitle:抗幽门螺杆菌治疗对慢性特发性血小板减少性紫癜患者疗效观察
- Author:
Honghua LI
;
Wanming DA
- Publication Type:Journal Article
- Keywords:
Idiopathic thrombocytopenic purpura\ Helicobacter pylori
- From:
Chinese Journal of Practical Internal Medicine
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Clinical research was made to observe the relationship between idiopathic thrombocytopenic purpura(ITP)and Helicobacter pylori(ITP)and to evaluate the effect of HP eradication in the treatment of chronic ITP.Methods ~(14)C urea breath test were made in 17 patients with chronic idiopathic thrombocytopenic purpura,including 6 males and 11 females,aging from 15-48,with course of disease from 4 months to 8 years.Omeprazole,clarithromycin and amoxicillin were used for Helicobacter pylori eradication,and the effect was evaluated by platelet count.Results Thirteen out of 17 patients were HP positive,and eleven turned negative after HP eradication,eight of whom were observed platelet recovery.Conclusion Platelet count can be raised in some patients with chronic ITP after eradication of Helicobacter pylori.