The research progress of cobra venom secretory phospholipase A_2
- VernacularTitle:眼镜蛇毒分泌型磷脂酶A_2的研究进展
- Author:
Yaping YANG
;
Zhongqin LIANG
;
Zhenlun GU
;
Zhenghong QIN
- Publication Type:Journal Article
- Keywords:
cobra venom;
secretory phospholipase A_2;
pharmacological effect;
tumor
- From:
Chinese Pharmacological Bulletin
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Cobra venom secretory phospholipase A_2 (sPLA_2) is an important component of cobra venom which has a variety of biological activities. Recent studies are mainly focusing on each pharmacological active component of venom, SPLA_2 is one of them. This review summarized the structure, purification and biological activities of cobra venom sPLA_2 with emphasizing its diverse pharmacological effects and toxicity. In addition, some mechanisms of actions of sPLA_2 and possible applications of sPLA_2 were also discussed.
