The protective effect of active components of isoflavones on the PC12 cells damage induced by A?_(1-42)
- VernacularTitle:异黄酮活性成分对A?_(1-42)诱导的PC12细胞损伤的保护作用
- Author:
Hong YANG
;
Yuhong ZHAO
;
Weiqiang CHEN
;
Shaohong LUO
;
Guifang JIN
;
Wei PAN
- Publication Type:Journal Article
- Keywords:
active components of isoflavones;
amyloid beta-protein;
PC12 cells
- From:
Chinese Pharmacological Bulletin
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim To study the effect of active components of isoflavones on PC12 cells damage induced with A?_(1-42). Methods The active components of isoflavones were extracted. Using PC12 cells damage induced by A?_(1-42) as the model,the protective effect of active components was determined with morphological examination and MTT and LDH assays. Results The morphological change of the damaged PC12 cells was improved, and the survival rate of the cells was significantly increased(P
