A retrospect of the research on optic nerve injury and regeneration after partial injury
- VernacularTitle:视神经损伤治疗和不全损伤再生研究的回顾
- Author:
Zhizhong MA
;
Houbin HUANG
- Publication Type:Journal Article
- Keywords:
optic nerve injuries;
nerve regeneration;
steroid;
decompression, surgical
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Optic nerve injury may occur at any section from the eyeball up to the brain. There should be enough mechanical power acting on the skull to result in severe optic nerve injury. Loss of light perception immediately after injury would be followed by an unfavorable prognosis. Efficacy of decompression procedures on optic nerve canal has not been demonstrated. large doses of adrenocortical steroid may be beneficial for early recovery of visual function. Based on the observation in animal model of partial injury, the capability of regeneration of optic nerve was closely associated with the extent of the injury. The enviroment for regeneration of partially injured optic nerve fibers is different from that of complete injury. The irreversibly injured fibers may have more regenerative potency than partially injured optic nerves.
