Significance of expression of c-met protein in gastric carcinoma and its correlation with MVD
- VernacularTitle:胃癌组织c-met蛋白表达的意义及其与微血管密度的关系
- Author:
Yongguo CAI
;
Dianchun FANG
;
Shiming YANG
- Publication Type:Journal Article
- Keywords:
proto-oncogene protein c-met;
micro-vessel density;
stomach neoplasms
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the significance of expression of c-met protein in gastric cancer tissue and to explore the correlation between c-met and micro-vessel density (MVD). Methods c-met protein and MVD in gastric cancerous tissue were determined by immunohistochemistry in 47 patients. Results The positive rate of c-met in gastric tissue was 85.1%. The expression of c-met was much higher in patients with tumor diameter larger than 5cm, with deeper invasion, regional lymph nodes metastasis, lymph vessel and venous invasion, and TNM stage Ⅲ-Ⅳ (P
