Effects of acupuncture at Tsusanli (He-Sea Point) on expression of FOS and GFAP in medullary visceral zone of rats under stress
- VernacularTitle:电针刺大鼠足三里穴对应激大鼠延髓内脏带内Fos和GFAP表达的影响
- Author:
Ming QIN
;
Yuxin HUANG
;
Jingjie WANG
- Publication Type:Journal Article
- Keywords:
acupuncture points;
genes, fos;
glial fibrillary acidic protein;
stress;
medulla oblongata
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of Fos gene and GFAP in medullary visceral zone (MVZ) of rats under stress with their gastric mucosa protected by acupuncture. Methods 24 male SD rats were randomly divided into 3 groups: control, stress and acupuncture group, with 8 for each group. Immunohistochemical methods were employed to detect the expression of Fos and GFAP in the nucleus of solitary tract (NTS) and dorsal motor nucleus of vagus (DMV) of medullary visceral zone. The extent of gastric mucosal damage was evaluated by ulcer index (UI). Results Fos-positive neurons and GFAP-positive stellar microgliocytes were found mainly in NTS and DMV of the medullary visceral zone. Compared with control group, the expression of Fos and GFAP was greatly up-regulated in the stress group, and UI increased obviously (P
