Study on the effect of cpd Danshen tablet combined with vitamin E in chronic hepatitis B(CHB)-related liver fibrosis
- VernacularTitle:复方丹参片联合维生素E对慢性乙型肝炎肝纤维化的影响研究
- Author:
Wuming KONG
;
Jun GONG
;
Lei DONG
- Publication Type:Journal Article
- Keywords:
Cpd shen tablet Vitamin E Liver fibrosis MMP
- From:
Chinese Journal of Practical Internal Medicine
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To probe the effect of Cpd danshen tablet combined with vitamin E in liver fibrosis by chronic hepatitis B.Methods 44 patients with CHB-related live fibrosis were allocated randomly into control group and Cpd danshen tablet combined with vitamin E treatment group for 6 months' treatment.Serum ALT,AST level and fibrosis markers including hyaluronic acid (HA),Ⅳ collagen(Ⅳ-C),amino terminal propeptide of type Ⅲ procollagen (PⅢP),and laminin(LN) and serum MMP1,2,TIMP1,2 level were determined before and after 6 months.Liver biopsies before and after 6 months were assessed.Results ALT,AST level in the two groups were decreased after 6 months' treatment(.P.
