Genotype-specific functional differences of the hepatitis B virus X protein
- VernacularTitle:乙型肝炎病毒X蛋白基因型特异性功能差异
- Author:
Xu LIN
;
Xiao XU
;
Qingling HUANG
- Publication Type:Journal Article
- Keywords:
Hepatitis B virus;
Genotype;
Trans Activation (genetics);
Colony-Forming units assay;
Apoptosis
- From:
Chinese Journal of Infectious Diseases
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
pcDNA3.1/Hygro(-)+pCMV?. Conclusions Transactivation competence of genotype B HBx was higher than that of genotype C HBx, while the antiproliferative and apoptosis effects of genotype B HBx was lower than of genotype C HBx. B and C genotype-specific functional differences of HBx may closely co-related with the pathogenicity of HBV.
