Effects of Astragalus polysaccharide and total glucosides of paeony on synergistic antiplatelet aggregation in rabbits
- VernacularTitle:黄芪多糖及其与白芍总苷协同对兔血小板聚集功能的影响
- Author:
Yi WEI
;
Tingting LIU
;
Tingting LIN
;
Yuyin LIU
;
Xiaoming SU
- Publication Type:Journal Article
- Keywords:
Astragalus polysaccharide;
total glucosides of paeony;
platelet aggregation;
uniform design;
synergistic action
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2004;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the interaction effects of Astragalus polysaccharide(APS) and total glucosides of paeony(TGP) with various dosage on the platelet aggregation. METHODS: Platelet aggregation was estimated by the turbidimetric method. The best interaction effects were determined by uniform design method. RESULTS: APS showed apparent anti-platelet effects and better combination with TGP,and the ratio of 121 was the best one. CONCLUSION: APS concerted with TGP inhibits platelet aggregation.
