The value of expression of telomerase reverse transcriptase gene in diagnosis of lung cancer patients.
- VernacularTitle:肺癌患者外周血单个核细胞hTERT基因表达在诊断中的价值
- Author:
Ping HE
;
Baogang WU
;
Naijing LI
- Publication Type:Journal Article
- Keywords:
Lung cancer Human telomerase reverse transcriptase Gene expression Diagnosis
- From:
Chinese Journal of Practical Internal Medicine
2002;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the significance of the expression levels of humans telomerase reverse transcriptase(hTERT) gene in peripheral blood mononuclear cells with lung cancer patients. Methods From Mar.2002 to Feb.2005,the expression levels of hTERT were detected in 30 lung cancer patients and 15 normal humans by quantitative measurement with RT-PCR. Results The expression levels of hTERT mRNA in lung cancer patients (0.906?0.112) were significant as compared with those health controls(0.407?0.104). Conclusion It is effective to diagnose lung cancer by the quantitative measurement with RT-PCR for the expression levels of hTERT mRNA.
