Down stage and long term results of preoperative chemoradiotherapy for locally advanced lower rectal cancer: a cooperative clinical trial of 6 institutions
- VernacularTitle:局部晚期低位直肠癌术前放化疗的降期效果和加前切除的远期疗效
- Author:
Jiandong LIU
;
Tonghai DU
;
Youhong CAI
;
Qi WANG
;
Xiude CAO
;
Xueheng GUO
- Publication Type:Journal Article
- Keywords:
Rectal neoplasms/chemotherapy;
Rectal neoplasms/radiotherapy;
Rectal neoplasms/surgery;
Prognosis
- From:
Chinese Journal of Radiation Oncology
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the down stage effect and long-term results of preoperative chemoradiotherapy for locally advanced lower rectal adenocarcinoma. Methods From Jan. 1989 to Jul 1999, 103 patients suffering from lower rectal carcinoma were treated. Criteria entry: 1. Distance between anal verge and centre of tumor 4-8?cm(median 6.2?cm), 2. Uncertainty in decision of preservation of anus before admission, 3. Lesion belonged to locally advanced type, 4. definitive pathology, clinical stage and presence of objective observation of tumor extent, 5. Performance status proposed by Eastern Cooperative Oncology Group 0-2, 6. Age0.05), 25.5% and 48.5% (P
