Interventional effects of hawthorn, konjac and their compound on the levels of lipid and NO in plasma of rats being induced to hyperlipidemia
- VernacularTitle:山楂、魔芋及其复合物对高脂血症大鼠脂质代谢及血浆NO水平的影响
- Author:
Dan HUANG
;
Yuangang SHI
- Publication Type:Journal Article
- Keywords:
hawthorn powder;
refined konjac flour;
compound;
hyperlipidemia;
lipid;
NO
- From:Journal of Third Military Medical University
2003;0(13):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of hawthorn powder, refined konjac flour and their compound on the levels of lipid and NO in plasma of rats being induced to hyperlipidemia by high-fat and high-cholesterol diet. Methods Fifty adult Wistar rats were randomly divided into five groups which were fed with normal diet, high-fat and high-cholesterol diet (HFD), HFD plus hawthorn powder, HFD plus refined konjac flour, HFD plus hawthorn and konjac compound, respectively. At week 4 and 8, 20 and 30 rats respectively were sacrificed for detecting the levels of lipid and NO in the blood. Results Hawthorn powder, refined konjac flour and their compound could significantly inhibit the increase of blood total cholesterol, triglycerol, VLDL-C, LDL-C induced by HFD and can significantly increase HDL-C and NO in plasma. Conclusion Hawthorn powder, refined konjac flour and their compound have the lipid-lowering effect. The hawthorn and konjac compound has better effects on increasing HDL-D and reducing VLDL-C. So they are beneficial to the prevention of atherosclerosis.
