Application of evidence-based medicine in evaluation of clinical trials in sepsis
- VernacularTitle:循证医学在脓毒症临床试验中的应用
- Author:
Yongming YAO
;
Hui LIU
;
Zhiyong SHENG
- Publication Type:Journal Article
- Keywords:
evidence-based medicine;
sepsis;
clinical trial
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Evidence-based medicine is also currently promoted and extolled as the best way to evaluate its various treatment and to draft clinical guidelines for the management of severe sepsis with aim to result in a reduction in mortality. There are several obvious factors in the design and conduct of clinical trials in sepsis to be observed, including case selection, end points, and sub-population evaluation, etc. In the past years, several scientific reports of evidence-based strategies for the treatment of sepsis were published, including recombinant human activated protein C, control of hyperglycemia in sepsis, and administration of low dose of corticosteroid in severe sepsis management.
