MR imaging findings of osteosarcomas treated with high intensity focused ultrasound
- VernacularTitle:MRI对高强度聚焦超声治疗骨肉瘤疗效的随访
- Author:
Huiyi YE
;
Wei WANG
;
Wenzhi CHEN
;
Lin MA
;
Youquan CAI
;
Zhibiao WANG
- Publication Type:Journal Article
- Keywords:
Osteosarcoma;
Ultrasonic therapy;
Magnetic resonance imaging
- From:
Chinese Journal of Radiology
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the usefulness of MR imaging in follow-up of osteosarcomas treated with high intensity focused ultrasound (HIFU). Methods The images of nonenhanced and multiphase gadolinium-enhanced MR imaging before and after HIFU treatment in 16 patients with osteosarcomas pathologically confirmed were interpreted prospectively and correlated with the results of ~ 99mTc-MDP bone scan. Results The results of HIFU in 14 osteosarcomas were evaluated correctly. Before HIFU, 16 osteosarcomas demonstrated hypointensity on T1WI and heterogenous hyperintensity on T2WI and obvious enhancement during capillary and delayed phases and abnormal radioactivity accumulation were detected.One to Four weeks after HIFU treatment, the osteosarcomas became slightly hyperintense on T1WI and heterogenously hyperintense on T2WI, and no enhancement during capillary and delayed phase was noted. There was a clear boundary presenting between the targeted and untreated areas, and abnormal radioactivity accumulation disappeared. Both the signal intensity on T2WI and the tumor size reduced gradually after HIFU treatment 3 to 25 months. Conclusion HIFU is an effective local therapy for osteosarcomas, and MRI can accurately evaluate the efficacy of HIFU.
