Increased carotid intima-media thickness in type 2 diabetes mellitus and risk factors.

VernacularTitle:2型糖尿病颈动脉内膜中层病变及相关危险因素分析
Author: Yan BI ; Dalong ZHU ; Yulu LIANG
Publication Type:Journal Article
Keywords: Type 2 diabetes mellltus Carotid intima media thickness C-reactive protein
From: Chinese Journal of Practical Internal Medicine 2001;0(07):-
CountryChina
Language:Chinese
Abstract: Objective To investigate the carotid intima-media thickness(C-IMT) in type 2 diabetes mellitus(T2DM) and the relationship with risk factors. Methods From 2002-01 to 2003-03, we measured C-IMT by B-mode ultra-sonography in 67 patients with different durations of T2DM. Blood was drawn from patients for the analysis of serum creatinine and C-reactive protein(CRP). 24-hour urine collection was performed to determine the level of urine creatinine clearance. Results C-IMT in patients increased with durations and with decreasing creatinine clearance. Multiple regression analysis revealed that C-reactive protein significantly and independently affected the C-IMT. Conclusion C-IMT increases with durations of T2DM and with BMI of the patients. CRP is the risk factor for carotid atherosclerosis in T2DM.